Zhiyuan Zhong Selected Research

caprolactone

1/2017	Targeted glioma chemotherapy by cyclic RGD peptide-functionalized reversibly core-crosslinked multifunctional poly(ethylene glycol)-b-poly(ε-caprolactone) micelles.
3/2015	Biodegradable glycopolymer-b-poly(ε-caprolactone) block copolymer micelles: versatile construction, tailored lactose functionality, and hepatoma-targeted drug delivery.
3/2014	Glyco-nanoparticles with sheddable saccharide shells: a unique and potent platform for hepatoma-targeting delivery of anticancer drugs.
10/2013	Ligand-directed reduction-sensitive shell-sheddable biodegradable micelles actively deliver doxorubicin into the nuclei of target cancer cells.
8/2013	Galactose-decorated reduction-sensitive degradable chimaeric polymersomes as a multifunctional nanocarrier to efficiently chaperone apoptotic proteins into hepatoma cells.
7/2013	Gold nanorod-cored biodegradable micelles as a robust and remotely controllable doxorubicin release system for potent inhibition of drug-sensitive and -resistant cancer cells.
8/2011	Galactose-decorated cross-linked biodegradable poly(ethylene glycol)-b-poly(ε-caprolactone) block copolymer micelles for enhanced hepatoma-targeting delivery of paclitaxel.

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Zhiyuan Zhong Research Topics

Disease

144	Neoplasms (Cancer) 03/2024 - 06/2007
21	Breast Neoplasms (Breast Cancer) 10/2022 - 05/2011
16	Lung Neoplasms (Lung Cancer) 01/2022 - 06/2015
14	Hepatocellular Carcinoma (Hepatoma) 10/2022 - 08/2011
12	Glioblastoma (Glioblastoma Multiforme) 11/2022 - 12/2014
11	Melanoma (Melanoma, Malignant) 10/2022 - 01/2017
7	Multiple Myeloma 11/2023 - 11/2017
7	Glioma (Gliomas) 01/2022 - 12/2014
6	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2024 - 10/2017
6	Neoplasm Metastasis (Metastasis) 12/2022 - 04/2019
5	Triple Negative Breast Neoplasms 07/2023 - 01/2017
5	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 01/2018
4	Prostatic Neoplasms (Prostate Cancer) 10/2023 - 04/2007
4	Inflammation (Inflammations) 03/2023 - 01/2015
3	Hematologic Neoplasms (Hematological Malignancy) 03/2023 - 11/2017
3	Bites and Stings (Sting) 01/2023 - 01/2022
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 01/2018
3	Body Weight (Weight, Body) 01/2021 - 01/2017
3	Colorectal Neoplasms (Colorectal Cancer) 10/2020 - 11/2018
3	Liver Neoplasms (Liver Cancer) 10/2020 - 03/2015
3	Myocardial Infarction 01/2017 - 04/2007
2	Leukemia 08/2023 - 10/2017
2	Rheumatoid Arthritis 03/2023 - 02/2022
2	Infections 01/2023 - 11/2022

Drug/Important Bio-Agent (IBA)

36	MicellesIBA 01/2022 - 10/2009
35	Peptides (Polypeptides)IBA 01/2023 - 07/2013
35	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2022 - 01/2009
25	Proteins (Proteins, Gene)FDA Link 01/2023 - 04/2007
23	Hyaluronic Acid (Hyaluronan)IBA 10/2021 - 06/2014
14	LigandsIBA 01/2022 - 10/2013
14	Ethylene Glycol (Monoethylene Glycol)IBA 10/2021 - 08/2011
13	IntegrinsIBA 10/2023 - 12/2014
13	DisulfidesIBA 10/2023 - 02/2017
12	Small Interfering RNA (siRNA)IBA 01/2023 - 04/2007
12	ProdrugsIBA 01/2022 - 05/2011
11	NanogelsIBA 04/2019 - 05/2011
10	Docetaxel (Taxotere)FDA Link 10/2023 - 07/2017
8	Paclitaxel (Taxol)FDA LinkGeneric 07/2023 - 03/2010
8	PolymersIBA 01/2022 - 04/2007
7	Transferrin (beta 2 Transferrin)IBA 01/2024 - 06/2014
7	CytokinesIBA 03/2023 - 01/2015
7	cyclic arginine-glycine-aspartic acid peptideIBA 01/2023 - 06/2014
7	caprolactoneIBA 01/2017 - 08/2011
7	Galactose (Galactopyranose)FDA LinkGeneric 09/2015 - 08/2011
6	Maytansine (Maitansine)IBA 12/2022 - 11/2016
5	ErbB Receptors (EGF Receptor)IBA 10/2022 - 07/2017
5	Glutathione (Reduced Glutathione)IBA 10/2022 - 11/2016
5	Granzymes (Granzyme)IBA 01/2022 - 06/2015
5	Apolipoproteins E (ApoE)IBA 01/2022 - 11/2018
5	Folic Acid (Vitamin M)FDA LinkGeneric 01/2022 - 06/2014
5	liposomal doxorubicin (Doxil)FDA Link 01/2018 - 10/2016
5	Liposomes (Liposome)IBA 01/2018 - 10/2012
5	polyethylene glycol bis(succinimidyl succinate)IBA 01/2017 - 08/2013
4	Vincristine (Oncovin)FDA LinkGeneric 08/2023 - 10/2021
4	AntigensIBA 08/2023 - 10/2021
4	Methotrexate (Mexate)FDA LinkGeneric 03/2023 - 09/2015
4	Messenger RNA (mRNA)IBA 01/2023 - 12/2018
4	Therapeutic UsesIBA 01/2023 - 06/2007
4	EnzymesIBA 09/2022 - 01/2018
4	Immunoconjugates (Immunoconjugate)IBA 12/2021 - 11/2018
4	DNA (Deoxyribonucleic Acid)IBA 10/2021 - 06/2010
4	Thioctic Acid (Lipoic Acid)IBA 11/2020 - 05/2015
4	Cytochromes c (Cytochrome c)IBA 10/2020 - 08/2016
4	AcidsIBA 01/2018 - 08/2013
4	HydrogelsIBA 07/2016 - 08/2007
3	VaccinesIBA 03/2024 - 10/2021
3	NanovaccinesIBA 03/2024 - 10/2021
3	Proteasome InhibitorsIBA 11/2023 - 10/2018
3	Immunologic Adjuvants (Immunologic Adjuvant)IBA 01/2023 - 01/2022
3	InterferonsIBA 01/2023 - 09/2022
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023 - 01/2018
3	Cancer VaccinesIBA 01/2023 - 10/2021
3	BI 6727IBA 09/2022 - 01/2021
3	acetyl- lysyl- prolyl- seryl- seryl- prolyl- prolyl- glutamyl- glutamic acid amideIBA 01/2022 - 01/2020
3	ApolipoproteinsIBA 01/2022 - 11/2018
3	Oncogene Proteins (Oncogene Protein)IBA 10/2021 - 12/2018
3	Nucleic AcidsIBA 10/2021 - 05/2011
3	SaporinsIBA 01/2020 - 07/2018
3	GE11 peptideIBA 01/2020 - 12/2017
3	IodineIBA 11/2019 - 01/2019
3	Cell-Penetrating PeptidesIBA 01/2019 - 01/2018
3	Matrix Metalloproteinases (MMPs)IBA 10/2017 - 01/2017
3	Glutamic Acid (Glutamate)FDA Link 11/2016 - 09/2015
2	carfilzomibIBA 11/2023 - 01/2020
2	daratumumabIBA 08/2023 - 10/2021
2	Gemcitabine FDA Link 07/2023 - 01/2022
2	MicroRNAs (MicroRNA)IBA 01/2023 - 10/2021
2	benzeneboronic acidIBA 01/2023 - 11/2022
2	Cetuximab (Erbitux)FDA Link 12/2022 - 10/2022
2	Radioisotopes (Radionuclides)IBA 11/2022 - 05/2019
2	Pemetrexed (MTA)FDA Link 10/2022 - 01/2018

Therapy/Procedure

72	Therapeutics 10/2023 - 10/2009
50	Drug Therapy (Chemotherapy) 10/2022 - 08/2011
12	Immunotherapy 03/2024 - 10/2021
4	Radiotherapy 01/2023 - 11/2019
4	Intravenous Injections 10/2022 - 12/2016
3	Precision Medicine 11/2022 - 12/2016
3	RNAi Therapeutics 10/2021 - 12/2018
3	Injections 01/2017 - 04/2007
2	Photochemotherapy (Photodynamic Therapy) 01/2023 - 11/2021